BMEWS
 
Sarah Palin's presence in the lower 48 means the Arctic ice cap can finally return.

calendar   Tuesday - April 14, 2020

never mind

I just killed a post that I spent hours on, trying to find some correlation for COVID cases here in NJ, based on county by county population, population density, county land size, whatever. I thought I had something, but I was wrong. So I killed the post.

I had churned a bunch of numbers I looked up, and made a graph. And it looked really neat. It was only later that I noticed that the data for the X axis was not displayed in increasing order. Once I fixed that, the graph went to hell. There is no smooth correlation between population density and the percentage of the population infected.

So, never mind. Oh, and as I’m not a professional spreadsheet jockey, I find making graphs to be counter intuitive in Excel. It sucks.

image

COVID infection rate as a percentage of the population of the counties in New Jersey





I think this graph shows only a loose correlation at best. Low population density areas are more likely to have lower infection rates as a percentage of the population than high population density areas, but the numbers are very wobbly. There is some other factor involved, and I have no idea what it is.

There ... at least that’s honest reporting on my part. I looked, I crunched, I didn’t get the results I thought I would.


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Posted by Drew458   United States  on 04/14/2020 at 07:48 PM   
Filed Under: • pandemic and epidemic diseases •  
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calendar   Thursday - April 09, 2020

Jumpin Jack Flash, It’s A Gas

Nitric Oxide Showing Promise As COVID-19 Treatment

Nitric oxide, not nitrous oxide (laughing gas). It helps relax the lungs so people can breath better. It’s been used to help premature “blue babies” to get their lungs working. Like so many other treatments being tested, it also has anti-viral properties. Every cell in your body makes it, but breathing some a couple times a day might really help, both as a cure and as a preventative.

Boston Massachussets:

A drug known to relax blood vessels could help coronavirus patients with severely damaged lungs and will be tested at Massachusetts General Hospital

The Boston hospital will be the first in the nation to rigorously test nitric oxide in coronavirus patients.

“It’s a pretty remarkable drug,” said Dr. Lorenzo Berra, the critical-care specialist at Massachusetts General who is overseeing the new, international trial. “It has a risk profile that is minimal.”

The study administers inhaled nitric oxide to patients with mild to moderate cases of the coronavirus. The gas is delivered through a CPAP breathing machine for 20-30 minutes twice a day.

“We have tremendous confidence this therapy will alter the devastating effects of COVID-19 but we must test it. If results show promise, and since this gas is already FDA-approved, widespread use could begin immediately,” said Dr. Keith Scott, principal investigator of the Louisiana component of the trial.

The trial will also test if the treatment could cut down on the number of patients who need a ventilator to breathe, as they are currently in short supply across the nation.

A proposed second trial that is being reviewed would enroll health care workers who are routinely exposed to coronavirus patients. Under that potential study, staff would inhale a high dose of the drug for 10 to 15 minutes at the start and end of every shift.

link to similar news article at LA Daily News



Birmingham Alabama:

The University of Alabama at Birmingham has been selected to begin enrolling patients in an international study assessing the use of inhaled nitric oxide to improve outcomes for COVID-19 patients with severely damaged lungs.

Acute respiratory distress syndrome, a severe form of lung failure, is the leading cause of death in COVID-19. Nitric oxide has been used for the treatment of failing lungs, but it was also found to have antiviral properties against coronaviruses, according to UAB officials.

The antiviral effect of nitric oxide was tested and demonstrated during the 2002-2003 SARS pandemic, which was caused by a similar coronavirus called the SARS-CoV virus.

“This trial will allow the sickest COVID-19 patients at UAB access to a rescue therapy that may have antiviral benefits in addition to improving the status of lungs,” said Dr. Vibhu Parcha, a research fellow with UAB’s Division of Cardiovascular Disease.

Dr. Pankaj Arora, assistant professor in the division, is spearheading UAB’s efforts in providing this treatment option to eligible COVID-19 patients.

“In humans, nitric oxide is generated within the blood vessels and regulates blood pressure, and prevents formation of clots and also destroys potential toxins,” Arora said.



Shreveport, Louisiana:

Critical care and emergency medicine faculty at the LSU Health Shreveport Department of Medicine join the Department of Anesthesia at Massachusetts General Hospital (MGH) and the Division of Cardiology in the Department of Medicine at University of Alabama-Birmingham (UAB) as being among the first centers in the U.S. to enroll patients in an international study testing using inhaled nitric oxide to improve outcomes for COVID-19 patients with severely damaged lungs; using gas to effectively “kill” corona virus in the lungs and improve delivery of oxygen to injured tissues.

“Inhaled nitric oxide had previously been suggested to decrease original SARS-CoV infectivity over a decade ago, but its effect on SARS-CoV2 [ aka COVID-19 ] remains unknown.  Moreover, research from LSU Health Shreveport has shown that nitric oxide is a strong protector against tissue hypoxia, which occurs during severe Covid-1 infection”, said Dr. Chris Kevil, Vice Chancellor for Research at LSU Health Shreveport.

...

Nitric oxide has already been a miracle drug for newborns starved of oxygen by a heart defect due to the gas’s ability to relax blood vessels, which ultimately led to the resolution of erectile dysfunction as targeted by the drug Viagra.

In 1992, the journal Science named nitric oxide “molecule of the year.” In addition, in 1998, UCLA pharmacologist Louis J. Ignarro shared a Nobel Prize in medicine for uncovering nitric oxide’s role as a “signaling molecule in the cardiovascular system.”



Italy:

In Italy during the COVID-19 outbreak the gas was used under less controlled study conditions; however the treatment appeared to dramatically boost oxygen levels in the blood of COVID-19 patients, said Dr. Lorenzo Berra, the critical-care specialist at Massachusetts General Hospital who is leading the new trial. However, it will take more rigorous testing to clarify how much nitric oxide helps, he said.

...

When inflammation, emphysema or a disease like cystic fibrosis attacks the lungs, the large blood vessels and tiny capillaries that deliver oxygen constrict. Inhaled nitric oxide also relaxes those vessels, increasing the transfer of oxygen to the blood and easing the heart’s workload.



Extra info:

As scientists race to find specific treatments for COVID-19, the colorless gas nitric oxide has emerged as a candidate.

Nitric oxide works as a signalling molecule in the cardiovascular, nervous and immune systems of animals, and is mostly produced in the inner layer of blood vessels called the endothelium. The compound relaxes muscle cells, which in turn prompts blood vessel walls to widen, boosting blood flow and decreasing blood pressure.

As such, physicians have used it for a range of conditions, and it was first approved for use by the U.S. Food and Drug Administration in 1999.

Warren Zapol, emeritus anesthetist-in-chief at Massachusetts General Hospital and a professor at Harvard Medical School, told Gizmodo nitric oxide is used to treat babies born blue, as well as adults with cardiac surgery, and patients with what is known as acute respiratory distress syndrome, where the oxygen supply to lungs are cut off by bodily fluids. “About a half-million Americans have breathed in NO [nitric oxide],” Zapol told the outlet.

~~~~

One very nice thing about the nitric oxide approach is that it can be delivered through a nasal cannula, or a CPAP or BiPaP machine and face mask. It does not have to be given via a ventilator. And the ventilators themselves may be doing more harm than good. Patients on them have an 80% fatality rate in NYC, and low surviveability rates elsewhere. With many other diseases, patients are only on the ventilators for a day or two, but with COVID-19 many are hooked up for two weeks. Ventilators are a rough treatment, and extended use may do more harm than good.

Generally speaking, 40% to 50% of patients with severe respiratory distress die while on ventilators, experts say. But 80% or more of coronavirus patients placed on the machines in New York City have died, state and city officials say.

Higher-than-normal death rates also have been reported elsewhere in the U.S., said Dr. Albert Rizzo, the American Lung Association’s chief medical officer.

Similar reports have emerged from China and the United Kingdom. One U.K. report put the figure at 66%. A very small study in Wuhan, the Chinese city where the disease first emerged, said 86% died.

The reason is not clear. It may have to do with what kind of shape the patients were in before they were infected. Or it could be related to how sick they had become by the time they were put on the machines, some experts said.

But some health professionals have wondered whether ventilators might actually make matters worse in certain patients, perhaps by igniting or worsening a harmful immune system reaction.

That’s speculation. But experts do say ventilators can be damaging to a patient over time, as high-pressure oxygen is forced into the tiny air sacs in a patient’s lungs.

“We know that mechanical ventilation is not benign,” said Dr. Eddy Fan, an expert on respiratory treatment at Toronto General Hospital. “One of the most important findings in the last few decades is that medical ventilation can worsen lung injury — so we have to be careful how we use it.”


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Posted by Drew458   United States  on 04/09/2020 at 11:19 AM   
Filed Under: • Health-Medicinepandemic and epidemic diseases •  
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calendar   Wednesday - April 08, 2020

It’s A Floor Wax AND A Dessert Topping

2500 French Cancer Patients Take Methylene Blue. Not One Gets COVID

Methelyne Blue is THE original synthetic medicine and was the first malaria drug back in 1891. It has been used to treat urinary tract infections (and turns your pee blue), has strong antiviral properties, was used to treat psychiatric patients and lead to the development of thorazine, and is used to dye samples for microscope slides. And it’s a fish tank cleaner.

Ok, just like Chloroquine Phosphate, it’s actually an aquarium medicine, but everybody is saying fish tank cleaner, so be it. It kills the fungus in the tank, and the slime on your fish, so close enough.

Oh, and chloroguine is made from methelyne blue. So there ya go.

Here’s another one of those “purely anecdotal” reports:

We report the case of a cohort of 2500 French patients treated among others with methylene blue for cancer care. During the COVID-19 epidemics none of them developed influenza-like illness. Albeit this lack of infection might be by chance alone, it is possible that methylene blue might have a preventive effect for COVID-19 infection. This is in line with the antiviral activity of Chloroquine, a Methylene blue derivative.

Both Chloroquine and Methylene blue have strong antiviral and anti- inflammatory properties probably linked to the change in intracellular pH and redox state.

Europe has been recently been hit by an epidemic of COVID-19. We report a cohort of patients treated for cancer in France. This cohort is managed by an association (Espoir Metabolique) and is a cancer support group. There are 2500 patients all at high risk for sepsis because of concomitant chemotherapy. One of us has interviewed (by telephone and by e mail) these patients to register the cases of COVID-19. As of March 27th, 2020, there were no cases of registered COVID-19 or of flu–like syndroms. These patients were treated by a combination of standard therapy and α-lipoic acid (800 mg twice a day), hydroxycitrate (500 mg three times a day) and methylene blue (75 mg three times a day) as well as a low carb diet.

Patients were also being treated with hydroxycitrate, which is a derivative of citric acid, commonly known as Vitamin C. Lipoic acid is made by most animals, and is needed for aerobic metabolism.

Cancer is another kind of disease able to lead to cytokines storms and one may expect a large number of deaths from COVID-19 in such patients. However, our survey among our database of patients treated with a combination of α-lipoic acid, hydroxycitrate and methylene blue suggests that this treatment prevents from severe infection from COVID-19. It may thus be anticipated, but yet not proved, that MB⊕ could be of considerable help for fighting against the COVID-19 epidemics. Here, we give a survey of the very interesting properties of this molecule with emphasis on chemistry, clinical trials being currently under investigation. Moreover, it is worth noting that methylene blue is the ancestor of modern anti-malaria drugs such as chloroquine and is associated to a lesser toxicity, the only drawback being a green-blue coloring of urine.

Following replication and sub-genomic RNA synthesis, the viral structural proteins S, E and M are translated and inserted into the endoplasmic reticulum (ER) for further processing by the endoplasmic reticulum-Golgi intermediate compartment (ERGIC). After encapsidation of the viral genome by the N-proteins in the ERGIC, budding with viral structural proteins (first with M and E, then with S later on) leads to mature virions. Following assembly, virions are transported to the cell surface in vesicles for further release by exocytosis.

If some S-proteins remain outside the virions, they may also transit towards the surface for mediating cell-cell fusion between infected cells and adjacent uninfected cells, leading to giant multinucleated cells, responsible for virus spreading without detection or neutralization by virus-specific antibodies. Accordingly, the primary determinant for infection of a cell by coronaviruses is the attachment of the virion through non-covalent interactions of protein-S with a suitable receptor. For human coronaviruses it is known that HCoV-OC43 binds to N-acetyl-9-O-acetylneuraminic acid, HCoV-HKU1 binds to O-acetylated sialic acids, while HCoV-NL63 and SARS-CoV bind to heparin sulfate proteoglycans.5 After binding to the cell, coronaviruses use a broad variety of fusion receptors: aminopeptidase N (APN) for HCoV-229E, human leucocyte antigen molecule (HLA class I) or sialic acids for HCoV-OC43, angiotensin-converting enzyme 2 (ACE2) for HCoV-NL63 and SARS-CoVs and dipeptyl-peptidase (DPP4) for MERS-CoV. The binding receptor of HCoV-HKU1 remains unknown. ACE2 receptors are expressed by epithelial cells of the lung, intestine, kidney and blood vessels, with a substantial upregulation in patients with type 1 or 2 diabetes or hypertension, who are treated by ACE inhibitors and angiotensin II type-I receptor blockers (ARBs).6 Increased expression of ACE2 is also observed by thiazolinidiones and ibuprofen. It has thus been inferred that people using ACE2-stimulating drugs may have a higher risk of developing severe and fatal COVID-19.

Then the paper gets really medical sciency. But you can follow along somewhat, sometimes. Like the “don’t take ibuprofen right now” part. “cytokine storms” get mentioned several times, lots of chemical formulas and molecular drawings. Bottom line - I think - is that all of these drugs raise the pH in the body, and the virus can’t handle that at all.

All these malaria drugs are made to be synthetic quinine, because there really isn’t all that many chincona trees out there. The original “fever tree”. And you do get a very minor amount of quinine in tonic water, although if you happen to have some powdered chincona bark (Amazon) you can make your own, quite strong. Although too strong can mess you up, so ignore this idea if you’re smart. Kind of wondering if some of that and some zinc supplements might do the job? Actually, everybody else has wondered this already, which is why there isn’t a drop of it on shelves anywhere. And you’d have to drink gallons of it a day, as the pills are wonderfully concentrated.



~~~~


Oh, and just for the hell of it ... the idea of treating COVID with chloroquine has been out there, in the West, online, since early February for the general public. The West had the Chinese study results since January 25:

Chloroquine, a widely-used anti-malarial and autoimmune disease drug, has recently been reported as a potential broad-spectrum antiviral drug.8,9Chloroquine is known to block virus infection by increasing endosomal pH required for virus/cell fusion, as well as interfering with the glycosylation of cellular receptors of SARS-CoV.10Our time-of-addition assay demonstrated that chloroquine functioned at both entry, and at post-entry stages of the 2019-nCoVinfection in Vero E6 cells(Fig.1c, d). Besides its antiviral activity, chloroquine has animmune-modulating activity, which may synergistically enhance its antiviral effect in vivo. Chloroquine is widely distributed in the whole body, including lung, after oral administration.

...

Our findings reveal that remdesivir and chloroquine are highly effective in the control of 2019-nCoV infection in vitro. Since these compounds have been used in human patients with a safety track record and shown to be effective against various ailments, we suggest that they should be assessed in human patients sufferingfrom the novel coronavirus disease.

this report was written by the coolest guy in China, Manli Wang. And Shi Zheng Li, both from the Wuhan Institute of Virology.

The USA had this information less than 10 days after there was just one known COVID-19 patient in the entire country. Just ONE. Link: the first known case was about 10 days after this report came out. Yes, at that point the threat was considered very low, but several US airports were already screening incoming passengers. On Trump’s watch. So “something was being done” even back then.


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Posted by Drew458   United States  on 04/08/2020 at 09:32 PM   
Filed Under: • Health-Medicinepandemic and epidemic diseases •  
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calendar   Tuesday - April 07, 2020

The ChiComs Even Screwed Up Our Numbers

Flattening the curve already? Awesome

NY: Cases Down 75%, Death Rate Flatlines

( sorry for that wretched pun )

Computer models predicted apocalypse, but the numbers are crap due to China’s lies.

The number of people hospitalized across the United States as a result of the novel coronavirus illness (COVID-19) is reportedly only a fraction of what some health experts projected a few days ago.

On Monday, New York Gov. Andrew Cuomo told reporters that in his state alone, the epicenter of the viral outbreak in the United States, new coronavirus hospitalizations dropped by about 75 percent, from 1,427 four days ago to 358 on Sunday.

Highlighting the drop in new hospitalizations in NY, the state hardest hit (131,239 cases; 4,758 deaths as of Monday) by the coronavirus, Alex Berenson, former New York Times reporter who has been following the U.S. outbreak closely, observed on Twitter on Monday: “It’s over, guys. It’s already over.”

Well, I wouldn’t go that far. And I wouldn’t grasp this thin straw as a lifeline. But still, it’s good news for today, and might be an “anecdotal” indication of better news tomorrow.

.@NYGovCuomo’s aide Jim Malatras says the projections are now showing that the state unlikely to need 110,000 beds for #Coronavirus.

New projections show MUCH LOWER demand, near 20,000-30,000 range if the new chart is believed.

— Jesse McKinley (@jessemckinley) April 6, 2020

That means the new projections for the number of hospital beds needed in NY are between about 70 and 80 percent lower than initially estimated.

On Monday, Gov. Cuomo acknowledged that the drop in hospitalizations in combination with other signs, like the fatalities remaining flat for the second day in a row and a drop in intensive care unit (ICU) admissions, suggest a “possible flattening of the curve.”

Statistical models attempting to predict the impact of the Chinese coronavirus, including the ones created by IHME, rely, at least in part, on polluted data from the Chinese Communist Party, Breitbart News confirmed last Friday.

A growing number of experts – including Vice President Mike Pence and members of the Whitehouse Coronavirus Task Force that he leads – have questioned the legitimacy of China’s official coronavirus death toll and infection rate.

Anonymous members of the U.S. intelligence community allegedly agree that China has been hiding the severity of the viral outbreak within its borders, under-reporting both total cases and fatalities linked to the disease, Bloomberg reported this week.

The IHME predictions for New York also reflected a discrepancy between the institute’s forecasts and the actual number of hospitalizations.

No word in the media as to why. Not even a maybe why. But NY did start trying HCQ about 16 days ago. Hmmm?



and of course, Obama’s Surgeon General, Vivek Murthy, gives HCQ the big meh. Maybe, maybe not. We need to do official long term trials to be certain. Same old same old.


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Posted by Drew458   United States  on 04/07/2020 at 11:43 AM   
Filed Under: • pandemic and epidemic diseases •  
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calendar   Monday - April 06, 2020

Trump Gets It Done, Again

Navy Hospital Ship In NYC Will Now Handle COVID Patients

The USNS Comfort, a hospital ship with about 1,000 beds that recently arrived in New York City, will soon be able to accept COVID-19 patients after it had originally been set up as an overflow facility for non-coronavirus patients.

President Trump said he spoke with New York Gov. Andrew Cuomo and New Jersey Gov. Phil Murphy and that both states plan to utilize the ship.

“New Jersey is a hot spot,” Mr. Trump said at the White House. “So Gov. Murphy and Gov. Cuomo are going to be using the ship…it’s set for COVID. Hopefully that will be very helpful to both states.”

“That is a welcome relief, and the president granted the request - he did it quickly,” Mr. Cuomo said on MSNBC.

“If you help me for New York, I will call it the way it is and say you delivered, and he delivered today,” Mr. Cuomo said. “And if I don’t think the federal government is meeting its responsibility, I’ll say that.”

The president swiftly granted a similar request last week to allow the Javits Convention Center in New York City, which has been set up as a makeshift 2,500-bed hospital, to accept coronavirus patients.

Both the Comfort and the Javits Center were originally supposed to be for non-COVID patients and had been intended to free up space for coronavirus patients at other hospitals as New York strains to accommodate the increased demand.



Governor Cuomo will probably be the “emergency shoe-in” candidate to replace senile dementia patient Joe Biden. Given the “emergency” I’m expecting he won’t even primary. The primaries are cancelled anyway. Bernie who?? They’ll simply take an applause vote at the convention ... if it actually gets held ... and give him the green light. So watch Cuomo shift from Big Gov Left Wing Radical to Man Of ALL The People over the next months. OTOH, the only way he’s going to get there is to play second fiddle to President Trump.


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Posted by Drew458   United States  on 04/06/2020 at 05:48 PM   
Filed Under: • pandemic and epidemic diseasesPandemic Pandemonium •  
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calendar   Thursday - April 02, 2020

Go To Hell

Governor HalfWhit the hypocrite now wants medicine she just denied the other day

Michigan Democratic Gov. Gretchen Whitmer’s administration has requested an emergency supply of the drugs President Trump touted as having success treating patients with severe symptoms of the novel coronavirus, in a reversal from the state’s directive to medical professionals last week to avoid the medication for this purpose.

Michigan, this week, requested hydroxychloroquine and chloroquine from the Strategic National Stockpile for physicians to use to help treat patients with COVID-19, after the Food and Drug Administration over the weekend granted an emergency use authorization for the anti-malarial drugs.

But last week, Whitmer’s administration threatened physicians prescribing the drugs, saying they were subject to “administrative action” should they continue to use the medication.

Actions have consequences. Michigan has had plenty of time to overthrow their governor by now. They haven’t, so to hell with them. Maybe I’m going stir-crazy from the isolation. Maybe I’ve just had it up to here with the hypocrisy, treason, and dirty politics. Fuck this woman, and fuck her entire state.

PK. I’ll soften that up. Having now proved her utter incompetence and her absolute lack of concern over the welfare of the people of Michigan, Governor Whitmer should immediately resign in disgrace. Then and only then can Michigan get some pills and some PPE gear. 


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Posted by Drew458   United States  on 04/02/2020 at 01:27 PM   
Filed Under: • Democrats-Liberals-Moonbat Leftistspandemic and epidemic diseasesREALLY WORTHLESS and PUTRID PEOPLE •  
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calendar   Tuesday - March 31, 2020

Gee, Too Bad

Drug Cartels Suffering, Raising Prices
Can’t get fentanyl from China right now

The onslaught of the coronavirus has not only sent the global economy tumbling – but it has also hit the black market where it hurts, and Mexican cartels are no exception.

The outbreak of COVID-19 has sent the price of heroin, methamphetamines, and fentanyl soaring as the likes of the Sinaloa cartel and its main rival the Jalisco “New Generation” struggle to obtain the necessary chemicals to make the synthetic drugs, which typically come from China but are now in minimal supply.

“The cartels have suffered from COVID-19 due to the inability to get the regular shipments of synthetic opioids and precursor chemicals for the massive production of meth from China,” Derek Maltz, a former special agent in charge of the Drug Enforcement Administration (DEA) Special Operations Division in New York, told Fox News. “The cartels have continued their production at a slower rate, but the demand seems to be increasing during these times of uncertainty in America. The shutdown of cities in China and travel in and out of China have also negatively impacted the flow of chemicals and drugs to Mexico.”

According to Maltz, the cartels have raised the prices of their products – as much as 400 percent – and “will get through the tough times,” especially since their business is so profitable.

Golly, that’s a terrible shame. And maybe with the borders closed somewhat more, they’re having a harder time smuggling it in as well. Sucks for them. Guess they’ll just have to try and get by with the hundreds of billions in cash they have sitting around.

I don’t think demand is going to decrease one bit. Junkies gotta junk, and will go without food or paying any other bills to spend what money they have on getting high. That’s what addiction means.

Quite a bit more at the link, describing changes to the cartels business model etc. 


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Posted by Drew458   United States  on 03/31/2020 at 09:08 AM   
Filed Under: • CrimeInflation and High Pricespandemic and epidemic diseases •  
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calendar   Monday - March 30, 2020

It Would Take A Miracle, Max

Sorry, this is a rough post. Actually, it started as an email paste and just got expanded a bit. And it’s 2am. Good night.

Doctor Vladimir Zelenko, Miracle Worker??

Rockland County NY, on the west side of the Hudson River across from Westchester County, and just 30 miles NW of NYC, currently has 2209 cases, and northern neighbor Orange County has 1247.

Dr. Vladimir Zelenko from Kiryas Joel. You know, the place up in Orange County that only had 14 cases? And also from Monsey NY… very likely from New Square or nearby. Both are very very similar communities, like Weschester’s New Rochelle NY and NJ’s Lakewood, only much moreso. Capice?

https://scontent.fagc1-2.fna.fbcdn.net/v/t1.0-9/s960x960/91123497_10158203091111774_6588351459786489856_o.jpg?_nc_cat=104&_nc_sid=110474&_nc_ohc=aPvbXr6xXP0AX-H0ayP&_nc_ht=scontent.fagc1-2.fna&_nc_tp=7&oh=bc4ea64888c01a5b5ea2ccd3f42ca799&oe=5EA4E252

Yeah, he’s treated 699 patients with HCQ ( Plaquenil )+ Z-Pack + Zinc and had 100% success. Well, at least with shortness of breath. Not much else mentioned at this point, except that nobody died or needed to be put on a ventilator.

“results within 4 to 6 hours”

In a video posted on YouTube, Dr. Vladimir Zelenko, a board-certified family practitioner in New York, said he saw the symptom of shortness of breath resolved within four to six hours.

Read more ... and this is from 2 days ago, referring back to results he shared a week before that

https://techstartups.com/2020/03/28/dr-vladimir-zelenko-now-treated-699-coronavirus-patients-100-success-using-hydroxychloroquine-sulfate-zinc-z-pak-update/
https://www.freerepublic.com/focus/f-news/3829531/posts
https://www.lohud.com/story/news/local/rockland/2020/03/19/kiryas-joel-video-coronavirus-spread-debunked/2879652001/

https://techstartups.com/2020/03/25/doctor-vladimir-zelenko-treated-350-coronavirus-patients-100-success-using-hydroxychloroquine-sulfate/

The whole treatment costs just $20.

the success story from Dr. Vladimir Zelenko, a board-certified family practitioner in New York, after he successfully treated 350 coronavirus patients with 100 percent success using a cocktail of drugs: hydroxychloroquine, in combination with azithromycin (Z-Pak), an antibiotic to treat secondary infections, and zinc sulfate.  Dr. Zelenko said he saw the symptom of shortness of breath resolved within four to six hours after treatment.

Now, Dr. Zelenko provides updates on the treatment after he successfully treated 699 COVID-19 patients in New York. In an exclusive interview with former New York Mayor, Rudy Giuliani, Dr. Vladmir Zelenko shares the results of his latest study, which showed that out of his 699 patients treated, zero patients died, zero patients intubated, and four hospitalizations.

Dr. Zelenko said the whole treatment costs only $20 over a period of 5 days with 100% success. He defines success as “Not to die.”

OTOH, others in the community really do wish he’d just pipe down for now. All the news is giving their members a bad rep and causing problems.

KIRYAS JOEL - Village leaders and community groups issued a joint statement on Tuesday rebuking a local doctor’s predictions about the spread of the coronavirus and urging him to stop posting videos online about the outbreak or else leave Kiryas Joel and the Hasidic community out of them.

The unusual public plea from the village’s main congregation, health center and other organizations came after Dr. Vladimir Zelenko recorded at least seven videos, including one that predicted a rampant spread of COVID-19 in Kiryas Joel and another that led Fox News host Sean Hannity to invoke the community on his radio and TV shows on Monday.

“We the undersigned institutions strongly believe that the predictions presented by Dr. Zelenko have been proven false and are not supported by the overall medical establishment, specifically in his wild conclusions as to the spread of the virus in our community,” the letter stated.

They said those statements had spurred discrimination against its residents and made it difficult to staff local businesses that remain open during the state emergency. Zelenko had estimated 90% of Kiryas Joel had COVID-19 after 9 of his first 14 tests came back positive — a conclusion the Orange County health commissioner blasted as irresponsible.

About 25,000 people live in the Kiryas Joel community. Last time I checked, they only had 14 cases officially. Now he’s treated nearly 700? Either he really REALLY gets around, or else the local rumors (that Kiryas has 75% of all the cases in Orange County) are pretty much true.

~~~~

But is Tulicizumab even better?
https://techstartups.com/2020/03/27/breaking-tolicizumab-shown-effective-hydroxychloroquine-treating-coronavirus-patients-doctors-say/

according to doctors treating coronovirus patients in Italy, Tolicizumab, a drug used to treat moderate to severe rheumatoid arthritis, has been shown to be more effective than hydroxychloroquine. Tolicizumab is so effective that the FDA gives green lights to Phase III Tocilizumab Trial for COVID-19 pneumonia. In a related report, Italian doctors said that a 101-year-old Italian man who survived the 1918 Spanish flu pandemic and World War II, recovered from COVID-19.

In another report, scientists claim Tocilizumab has been shown to help cure 95 percent of critically ill coronavirus patients in China. Tocilizumab, which is marketed as Actemra, is taken by patients with rheumatoid arthritis to reduce inflammation. Chinese doctors gave it to 20 patients during the peak of of coronavirus epidemic. Nineteen of the patients were discharged within 14 days despite being critically ill. Actemra has now been approved for use in China and for trials in the US

...

Tocilizumab, also known as atlizumab, is an immunosuppressive drug, mainly for the treatment of rheumatoid arthritis (RA) and systemic juvenile idiopathic arthritis, a severe form of arthritis in children. It is a humanized monoclonal antibody against the interleukin-6 receptor (IL-6R).

I guarantee you Actemra costs a whole lot more than generic Plaquenil and generic Z-Pack. And some vitamin pills. Yeah, I picked up on the zinc angle a couple weeks back. Vitamin C and D too, also rumored to help. Taking selenium, another metallic supplement, was an earlier rumor.

~~~~

Not really related to this at all ... but little Putnam County NY, just north of Westchester (which has 8519 cases, 2nd in the nation only to it’s southern neighbor NYC), has a mere 142 cases. How is this possible?  Both counties are populous bedroom communities; commuters to NYC. Right across the Hudson, Orange County is also one these days, although it was the back of beyond as recently as 1985. Rockland has always been, ever since the bridges opened.
https://www.lohud.com/story/news/politics/2020/03/21/coronavirus-new-york-map-cases-by-county/2891036001/


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Posted by Drew458   United States  on 03/30/2020 at 12:38 AM   
Filed Under: • Health-Medicinepandemic and epidemic diseasesPandemic Pandemonium •  
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calendar   Friday - March 27, 2020

Livin On The Edge

We salute you, Captain Obvious

The Northeast isn’t that big an area, but a whole lot of people live here.

I looked at some of those coronavirus numbers in a bit of detail this morning. It reminds me of those nuclear fallout drawings we used to see back in the day.

The vast majority of confirmed cases in the USA are within a 100 mile radius of New York City and within a 50 mile radius of Boston.

The news is full of the counts on a state by state basis, but if you look a little closer at the county level you’ll see the real story.

NY: 38,977
NJ: 6876
MA: 2417
PA: 1718
CT: 1012
-----------
51,000

Entire USA: 69,246

That means that 73.65% - nearly three quarters - of all the cases are in these 5 states. 3 out of 4 cases. Crivens.

However, a huge portion of those cases are close to those two major metropolitan areas. Most of the rest of them are centered around the other minor metro areas like Philadelphia and Buffalo.

Out here in the “sticks” of rural NW NJ, Hunterdon County has 39 cases today. [ 6pm update: FUCK. We just got the automated emergency phone call. Now it’s 60 cases. That’s a 50% increase since this morning. ] Warren County, the next county up and even more rural, has 31. Down in the low population, even more rural, SE corner of the state, the combined total for Atlantic, Cumberland, Salem, and Cape May Counties is 22.

22. There are apartment buildings in NYC with more cases than that. Lack of testing could be a factor here, but I have my doubts.

The NJ counties closest to NYC have the most cases.

New York has a similar situation. New York City is the big one, with the four nearby counties of Westchester, Rockland, Nassau, and Suffolk having significant numbers, and moderate numbers up in Orange County, but the four smaller cities of Buffalo, Rochester, Syracuse, and Albany have their own minor zones too. The rest of the state has very few infections.

Pennsylvania’s cases are centered around Philadelphia, with most of the counties along the Delaware River border with NJ showing the larger numbers. All of those counties are within the commuting zone to both NYC and Philly. Pittsburgh, out in Allegheny County, is it’s own minor hot spot.

It’s only 80 miles as the corona crow flies from New York City to Philadelphia.

The same situation holds true in Connecticut and Massachusetts. Even in New Hampshire, most of the cases are within 50 miles of Boston.

It will be very interesting, and rather frightening, to see if this wave spreads outwards with time, or if the lower population density and all this lockdown stuff provides a buffer. Or how the situation will change once tens of millions of fast tests come into use across the nation.

I probably have about 2 weeks until the wave hits here. Wonderful.




Related Update: New York State In Total Lockdown. Press release given at the poorly chosen time of 9:11am: 100% of the workforce must stay home if non-essential




This is also obvious. And true. When can we lamp-post the enemedia?

image


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Posted by Drew458   United States  on 03/27/2020 at 10:29 AM   
Filed Under: • pandemic and epidemic diseases •  
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Viral Career Killer

Dem Michigan Governor Threatens Doctors For Chloroquine

I kind of wonder if she has any actual authority here, but if this stuff works then “I left you to die!!” is the worst re-election slogan in history.

Gov. Gretchen Whitmer’s Department of Licensing and Regulatory Affairs warns that prescribing hydroxychloroquine or chloroquine for treatment of COVID-19 ‘without further proof of efficacy’ may be investigated for administrative action; reaction from Dr. Jeff Colyer, former Kansas governor.

Excerpt from the letter sent out by the Michigan BPL:

TO:  Licensed Prescribers & Dispensers
RE:  Reminder of Appropriate Prescribing and Dispensing

Dear Licensed Prescribers and Dispensers:The Department of Licensing and Regulatory Affairs has received multiple allegations of Michigan physicians inappropriately prescribing hydroxychloroquine or chloroquine to themselves, family, friends, and/or coworkers without a legitimate medical purpose.

Prescribing hydroxychloroquine or chloroquine without further proof of efficacy for treating COVID-19 or with the intent to stockpile the drug may create a shortage for patients with lupus, rheumatoid arthritis, or other ailments for which chloroquine and hydroxychloroquine are proven treatments. 

Reports of this conduct will be evaluated and may be further investigated for administrative action. 

Prescribing any kind of prescription must also be associated with medical documentation showing proof of the medical necessity and medical condition for which the patient is being treated. 

Again, these are drugs that have not been proven scientifically or medically to treat COVID-19.Michigan pharmacists may see an increased volume of prescriptions for hydroxychloroquine and chloroquine and should take special care to evaluate the prescriptions’ legitimacy.

Pursuant to Michigan Administrative Code, R 338.490(2), a pharmacist shall not fill a prescription if the pharmacist believes the prescription will be used for other than legitimate medical purposes or if the prescription could cause harm to a patient

In addition to whatever stock on hand is in the US, Teva has donated 6 million pills, Bayer AG has sent us 3 million, Novartis has 50 million on hand and will churn out another 80 million by the end of May, and the FDA has added HCQ to the Interim Policy list, which will allow generic pharma companies and even pharmacies to make the stuff.

All told, there is probably enough out there right now to treat 4 million people. With lots more coming. So there is no shortage at all, and no hoarding necessary. Just keep the distribution channels running. Since the treatment plan is less than a week, we should have trials results data real soon. Provided, of course, that the media bothers to report it.

~~

You may remember Governor Whitmer. She’s the one who gave the Dem rebuttal to President Trump’s magnificent SOTU address back in February.

“It’s pretty simple. Democrats are trying to make your health care better. Republicans in Washington are trying to take it away,” Whitmer said in prepared remarks.

Uh huh. That is pretty simple: she’s a total lying hypocrite.



~~~~



Meanwhile, this EVIL DRUG that TRUMP IS POISONING EVERYONE WITH is showing success in Belgium and Bahrain. Phhhbbtt. Foreigners, what do they know about anything? It’s up to MI Governor Whitmer to block this for your own good.

Bahrain and Belgium report their hospitals are successfully treating coronavirus patients with the anti-malaria drug hydroxychloroquine touted by President Trump as a possible breakthrough in the pandemic.

The Kingdom of Bahrain’s Supreme Council of Health chairman said his country was among the first to use the drug and that its impact has been “profound,” according to the Bahrain News Agency.

Dr. Shaikh Mohamed, who leads the National Taskforce for Combating COVID-19, was also quoted by the news agency as saying hydroxychloroquine was administered according to the same regimens as those used in China and South Korea.

The first COVID-19 case in Bahrain was reported on Feb. 21, and hydroxychloroquine was first administered to patients showing virus symptoms on Feb. 26. As of March 25, the virus had caused 4 deaths in Bahrain, according to the Johns Hopkins Coronavirus Resource Center. 

...

Meanwhile in Europe, another U.S. ally, Brussels, is reporting similar early success with the same drug and is taking steps to ensure its availability for the sickest coronavirus patients.

“Using the limited stocks of these medicines for unnecessary or unjustified preventive treatments jeopardizes the availability of these medicines for patients who need them: chronic patients and hospital patients seriously affected by Covid-19,” Belgium’s Federal Agency for Medicines and Health Products said this week.

Belgium, like the United States, has begun a longer-term clinical trial on the efficacy of using Hydroxychloroquine to treat COVID-19 patients.

While warning against hoarding, and saying that this treatment plan is not yet proven or even fully tested, Belgium is delivering enough to treat 22,000 patients to each of their hospitals, with enough in the next delivery to treat another 17,000. There are 7,284 cases in the whole country.

Sounds like they are giving it a serious try. 


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Posted by Drew458   United States  on 03/27/2020 at 07:07 AM   
Filed Under: • Health-Medicinepandemic and epidemic diseasesPandemic Pandemonium •  
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calendar   Tuesday - March 24, 2020

Must Be A Coincidence

Today’s News:

New York City has nearly half the Wuhan virus cases in the country

New York Gov. Andrew Cuomo issued a sobering warning to residents on Tuesday as he said that the coronavirus curve hasn’t been “flattened,” and “is actually increasing.” He then cautioned that the apex of the virus could be as many as 14 to 21 days away.

“We projected an apex at 100,000 hospital beds needed, the new projection suggests as high as 140,000 hospital beds will be needed,” he said, adding that New York has 25,000 confirmed cases of COVID-19.





Six Weeks Ago:

image   image

Tens of thousands gather to celebrate Chinese New Year in New York City

[ February 9, 2020 ] NEW YORK (AP)—Signs of support for the Chinese city at the center of a global virus outbreak marked floats at the Lunar New Year parade in Manhattan’s Chinatown.

Brightly colored puppets made their way through the New York City streets Sunday in front of crowds of onlookers.

A banner on one float read “Support Wuhan! Let’s fight the virus together!” Another urged, “Wuhan stay strong.”

The coronavirus outbreak that started in China in December has killed more than 800 people and infected more than 37,000 people around the world.

No cases have been identified in New York City.

https://twitter.com/DeplorableShay/status/1241950593666682883/photo/1

“If you’re not here, you’re missing out!”

Nearly 3/4 million Chinese live in the NYC metro area; more than half a million of them live within the 5 boroughs.

The news only gives us numbers. It does not say what groups those numbers belong to. Once in a while we hear about one identified person’s story, or some celebrity who has caught it.

Northern Italy also has a tremendous population of Chinese laborers; nearly half a million of them all told. And they’ve been hit really hard too. That’s probably another coincidence. Nothing to see here, move along.


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Posted by Drew458   United States  on 03/24/2020 at 04:22 PM   
Filed Under: • pandemic and epidemic diseases •  
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calendar   Thursday - March 19, 2020

As Expected, Trump Makes It Happen

President Trump: Move Forward With Plaquenil Right Now

President Trump announced Thursday that the Food and Drug Administration (FDA) is making experimental drugs—including those used for treating malaria -- available as part of the ongoing effort to tackle the spread of the coronavirus.

Trump announced at a White House press briefing that chloroquine, a drug designed for use in malaria, has been FDA approved and will be made available by prescription “almost immediately.” He said it was one of a number of antiviral therapies to limit the symptoms of the virus that the administration is trying to get to Americans as quickly as possible.

“I have directed the FDA to eliminate rules and bureaucracy so work can proceed rapidly, quickly and fast,” he said. “We have to remove every barrier.”

Addressing potential safety concerns, Trump noted that it had been used previously in treating malaria, “so we know if things don’t go as planned, it’s not going to kill anybody.” He said it had shown “very encouraging” early results.

He also said another drug, remdesivir, would be made available to Americans as well by the process of “compassionate use.” He said it would remain to be seen whether it would help combat the crisis.

So while the President did actually specifically say “chloroquine”, it’s pretty much a guarantee that he meant hydroxychloroquine sulfate, which is the common drug Plaquenil. To us laymen, it’s all chloroquine, although there are two forms of it, and the new NIH study did indicate that HCQ was much more effective. See yesterday’s posts.

U.S. researchers, following the lead of scientists in other countries, have launched studies to see whether widely-available, low-cost generic drugs can be used to help treat the illness caused by the new coronavirus.
...
... a 1,500-person trial, led by the University of Minnesota, began this week to see whether malaria treatment hydroxychloroquine can prevent or reduce the severity of COVID-19. Two other trials are studying the blood pressure drug losartan as a possible treatment for the disease.

The malaria drug, also being tested in China, Australia and France ...

Besides having a direct antiviral effect, hydroxychloroquine suppresses the production and release of proteins involved in the inflammatory complications of several viral diseases.

There was a report out of China recently that a test of 100 ailing subjects given Kaletra showed barely any positive effects (1 in 100), and bad reaction to that HIV medicine’s combination of lopinavir and ritonavir forced 13.8% off the mediction. Remdesivir is not the same as ritonavir.

This is most likely part of the WHO’s worldwide guinea pig large scale in-situ test of multiple solutions

The World Health Organization is taking the drug-testing approach that helped stifle Ebola’s latest resurgence and using it against the new coronavirus.

At least 10 countries including France, Spain and Switzerland agreed to join a trial called Solidarity that the global agency is coordinating, simultaneously testing four therapies by pitting them against each other.

The strategy is designed to speed up a process that can take years as doctors scour laboratories for promising treatments against the new virus.
...
In the Solidarity trials, researchers will test four therapies, some of which are already used in people, to treat Covid-19: Gilead Sciences Inc.’s experimental remdesivir, AbbVie Inc.’s Kaletra (used to treat HIV infection), Kaletra with an anti-inflammatory treatment called interferon-beta, and the malaria drug chloroquine.

China has included chloroquine in treatment recommendations for Covid-19. Ongoing studies showed that Kaletra, a combination of the drugs lopinavir and ritonavir, gave little benefit, according to early results published Wednesday in the New England Journal of Medicine. Additional medicines may be added and some of the original treatments may be cut out as the trial progresses.

https://townhall.com/tipsheet/leahbarkoukis/2020/03/19/fox-interview-malaria-drug-to-treat-n2565260


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Posted by Drew458   United States  on 03/19/2020 at 12:06 PM   
Filed Under: • Health-Medicinepandemic and epidemic diseases •  
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calendar   Wednesday - March 18, 2020

And We Have A Cure?

Breaking News, Kind Of

Claim: Plaquenil and Z-Pack Cures COVID-19 100% In 6 Days

Study done via NIH, released a couple days ago finds that hydroxycholorquine much more effective in vitro than choloroquine:

According to the study, the researchers tested the pharmacological activity of chloroquine and hydroxychloroquine using SARS-CoV-2 infected Vero cells. They then implemented physiologically-based pharmacokinetic models (PBPK) for both drugs separately by integrating their in vitro data. Using the PBPK models, hydroxychloroquine concentrations in lung fluid were simulated under 5 different dosing regimens to explore the most effective regimen whilst considering the drug’s safety profile.

Based on PBPK models results, a loading dose of 400 mg twice daily of hydroxychloroquine sulfate given orally, followed by a maintenance dose of 200 mg given twice daily for 4 days is recommended for SARS-CoV-2 infection, as it reached three times the potency of chloroquine phosphate when given 500 mg twice daily 5 days in advance.



[ Splitting hairs here. It turns out that the “coronavirus” we’re all going crazy about not only is just one of thousands of coronaviruses, but it is also a variation of the SARS virus. Specifically, the disease is the SARS-CoV-2 virus, and COVID-19 is the illness/symptoms created by the virus. For all of us normies, the terms are interchangeable. ]

Meanwhile in France ... a preliminary?? study of 40 patients ... (although the Chinese, South Koreans etc have been using this for awhile)

BREAKING: New controlled clinical study conducted by doctors ​in France shows that Hydroxychloroquine cures 100% of coronavirus patients within 6 days of treatment

a recent well controlled clinical study conducted by Didier Raoult​ M.D/Ph.D, et. al in France showed that 100% of patients that received a combination of HCQ and Azithromycin tested negative and were virologically cured within 6 days of treatment.

In addition, recent guidelines from South Korea and China report that hydroxychloroquine and chloroquine are effective antiviral therapeutic treatments for novel coronavirus.

A therapeutic agent that prevents infection with novel coronavirus is highly desirable–especially for persons with high-risk exposure (e.g healthcare professionals) as well as persons with comorbidities (heart disease, diabetes, etc) and compromised immune systems. Ground-breaking in vitro studies demonstrate potential efficacy of hydroxychloroquine as a prophylactic for novel coronavirus infection in primate cells.

Note: Hydroxychloroquine (brand name Plaquenil) is an inexpensive, globally available drug (tablet) that was approved for widespread medical use since 1955. It is commonly used today to treat malaria, systemic lupus erythematosus and rheumatoid arthritis.

The study is part of the initiative from an independent group of scientists and physicians working on an open-data clinical trial for prevention of COVID-19, through the use of hydroxychloroquine in combination with other therapeutic agents. The group is now calling on President Trump to allow Americans to use the drug.

HCQ is hydroxychloroquine, the pill called Plaquenil, and Azithromycin is the antibiotic commonly known as the Z-pack. Z-pack hit the market 29 years ago as a respiratory treatment antibiotic, but has proven very effective against many other illnesses too.



I am thrilled to hear this, and even more thrilled to hear that a cheap common RA drug combined with a cheap common antibiotic appears to be highly effective; while other reports have shown that HCQ along with the (very expensive, >$500) HIV combo drug Kaletra (Lopinavir and Ritonavir)

HCQ also appears to be very effective at keeping you from getting this damn thing in the first place.


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Posted by Drew458   United States  on 03/18/2020 at 09:09 PM   
Filed Under: • Health-Medicinepandemic and epidemic diseasesPandemic Pandemonium •  
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calendar   Tuesday - March 17, 2020

Give Us Your Blood (to test, and later when you’re recovered, to share with others still sick)

Plasma From Recovered COVID Patients May Help Those Still Sick: China Testing It, WHO Agrees

This is on the news tonight, but has been out there online, buried under the hysteria, for a month now. Gee, I wonder why?

You get sick, your body makes antibodies, you get well. Those antibodies are in your blood. Filter the blood cells out of blood and you’re left with plasma. Which has the antibodies ... which may not be personally unique to each patient? Your antibodies will cure me? A lot of the time, this works. Plasma therapy is nothing new; it’s been done for quite some time now.

SHANGHAI/GENEVA (Reuters) - Doctors in Shanghai are using infusions of blood plasma from people who have recovered from the coronavirus to treat those still battling the infection, reporting some encouraging preliminary results, a Chinese professor said on Monday.

A top emergency expert at the World Health Organization (WHO) said later that using convalescent plasma was a “very valid” approach to test, but that it was important to get the timing right to maximize the boost to a patient’s immunity.

...

There are no fully licensed treatments or vaccines against the new coronavirus, and the process of developing and testing drugs can take many months and even years.

Convalescent plasma has been proven “effective and life-saving” against other infectious diseases, including rabies and diphtheria, Dr. Mike Ryan, head of WHO’s health emergencies program, told reporters in Geneva. “It is a very important area to pursue,” Ryan said.

“Because what hyperimmune globulin does is it concentrates the antibodies in a recovered patient. You are essentially giving the new victim’s immune system a boost of antibodies to hopefully get them through the very difficult phase.

“So it must be given at the right time, because it mops up the virus in the system, and it just gives the new patient’s immune system a vital push at the time it needs it. But it has to be carefully timed and it’s not always successful.”

~~~~

Testing, testing, testing

Acceptably Accurate 15 and 10 Minute Tests

[ February 17 2020 ] Chinese scientists have created a new diagnostic method using blood serum that can produce accurate results in 15 minutes and greatly reduce the exposure of medical workers to ill patients.

The new test kit is called novel coronavirus IgM antibody, and it has finished preliminary evaluation in lab and clinical tests, the State Key Laboratory of Respiratory Disease in Guangdong province said.

[ March 17, 2020 ] COVID-19 IgG/IgM Rapid Test Device by Caming Pharmaceutical, sold by Watson International

COVID-19 IgG/IgM Rapid Test Device is a rapid chromatographic immunoassay for the qualitative detection of IgG & IgM antibody of COVID-19 IgM in human whole blood , serum, or plasma as an aid in the diagnosis of COVID-19 infections.

This kit uses immunochromatography. The test card contains: 1) colloidal gold-labeled recombinant new coronavirus antigen and quality control antibody gold markers; 2) two detection lines (G and M lines) and one quality Control line (C line) of nitrocellulose membrane. The M line is immobilized with a monoclonal anti-human IgM antibody for detecting a new coronavirus IgM antibody; the G line is immobilized with a reagent for detecting a new coronavirus IgG antibody; and the C line is immobilized with a quality control antibody.

All a tech needs to do is add a few drops of blood and 2 drops of buffer solution to the simple disposable device. It’s like one of those early pregnancy test things, but with serum instead of urine. It tests both antibody lines and has a control test to show if the tech screwed up. Results in 10 minutes. So it’s really fast. It’s 100% accurate on healthy people, and 90.5% - 96% accurate on infected people. Not perfect, but a damn site better than nothing, and a LOT less invasive than the older test that needs a lung fluid sample. For susceptible people the test is 70 - 74.5% accurate, whereas the older test isn’t even applicable (0% accuracy). Testing in China shows the false positive rate for this group to be extremely low.

The current CDC test uses a swab from upper and lower respiratory tract.

A laboratory test produced by the Centers for Disease Control and Prevention is currently being used for COVID-19 testing in the United States. This test requires a swab from the patient’s nose or throat and lungs and is available at CDC-designated locations in the United States and qualified international laboratories.

There are two main elements to a COVID-19 test, according to interim guidelines shared publicly by the CDC to clinicians.

The coronavirus is a respiratory disease, so the test kits take specimens from both the upper and lower respiratory tracts.

Tests in the lower respiratory tract include a branchoalveolar lavage, a minimally invasive procedure in which the clinician places a bronchoscope through the patient’s mouth or nose and into the lungs. A sterile fluid solution is squirted into a small part of the lung, and a specimen is collected for examination.

The patient then produces a sputum sample: “Have the patient rinse the mouth with water and then expectorate deep cough sputum directly into a sterile, leak-proof, screw-cap sputum collection cup or sterile dry container,” the CDC’s instructions read.

In the second test, for the upper respiratory tract, the clinician will swab the patient’s nostril as well as the throat. The test also collects a 2 to 3 milliliter specimen following a nasal “wash” or aspirate, which involves a soft, flexible tube in the nose.

These specimens are refrigerated until they can be shipped to the CDC for testing.

The kit is to be stored at 35-46 degrees Fahrenheit and kept at that temperature using an ice pack or dry ice as it is shipped to a CDC lab.
...
The CDC does not specify the time frame for which results should be expected, but its guidelines call for the samples to be shipped overnight.

In the case of the patient being treated at UC Davis Medical Center, the positive diagnosis appears to have been received about three days after testing.

And when they’re swamped with tests, it’s going to take a lot longer than 3 days to get the results. So a 10 minute test is one helluva improvement.


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Posted by Drew458   United States  on 03/17/2020 at 08:57 PM   
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