Wednesday - March 18, 2020

And We Have A Cure?

Breaking News, Kind Of

Claim: Plaquenil and Z-Pack Cures COVID-19 100% In 6 Days

Study done via NIH, released a couple days ago finds that hydroxycholorquine much more effective in vitro than choloroquine:

According to the study, the researchers tested the pharmacological activity of chloroquine and hydroxychloroquine using SARS-CoV-2 infected Vero cells. They then implemented physiologically-based pharmacokinetic models (PBPK) for both drugs separately by integrating their in vitro data. Using the PBPK models, hydroxychloroquine concentrations in lung fluid were simulated under 5 different dosing regimens to explore the most effective regimen whilst considering the drug’s safety profile.

Based on PBPK models results, a loading dose of 400 mg twice daily of hydroxychloroquine sulfate given orally, followed by a maintenance dose of 200 mg given twice daily for 4 days is recommended for SARS-CoV-2 infection, as it reached three times the potency of chloroquine phosphate when given 500 mg twice daily 5 days in advance.

[ Splitting hairs here. It turns out that the “coronavirus” we’re all going crazy about not only is just one of thousands of coronaviruses, but it is also a variation of the SARS virus. Specifically, the disease is the SARS-CoV-2 virus, and COVID-19 is the illness/symptoms created by the virus. For all of us normies, the terms are interchangeable. ]

Meanwhile in France ... a preliminary?? study of 40 patients ... (although the Chinese, South Koreans etc have been using this for awhile)

BREAKING: New controlled clinical study conducted by doctors ​in France shows that Hydroxychloroquine cures 100% of coronavirus patients within 6 days of treatment

a recent well controlled clinical study conducted by Didier Raoult​ M.D/Ph.D, et. al in France showed that 100% of patients that received a combination of HCQ and Azithromycin tested negative and were virologically cured within 6 days of treatment.

In addition, recent guidelines from South Korea and China report that hydroxychloroquine and chloroquine are effective antiviral therapeutic treatments for novel coronavirus.

A therapeutic agent that prevents infection with novel coronavirus is highly desirable–especially for persons with high-risk exposure (e.g healthcare professionals) as well as persons with comorbidities (heart disease, diabetes, etc) and compromised immune systems. Ground-breaking in vitro studies demonstrate potential efficacy of hydroxychloroquine as a prophylactic for novel coronavirus infection in primate cells.

Note: Hydroxychloroquine (brand name Plaquenil) is an inexpensive, globally available drug (tablet) that was approved for widespread medical use since 1955. It is commonly used today to treat malaria, systemic lupus erythematosus and rheumatoid arthritis.

The study is part of the initiative from an independent group of scientists and physicians working on an open-data clinical trial for prevention of COVID-19, through the use of hydroxychloroquine in combination with other therapeutic agents. The group is now calling on President Trump to allow Americans to use the drug.

HCQ is hydroxychloroquine, the pill called Plaquenil, and Azithromycin is the antibiotic commonly known as the Z-pack. Z-pack hit the market 29 years ago as a respiratory treatment antibiotic, but has proven very effective against many other illnesses too.

I am thrilled to hear this, and even more thrilled to hear that a cheap common RA drug combined with a cheap common antibiotic appears to be highly effective; while other reports have shown that HCQ along with the (very expensive, >$500) HIV combo drug Kaletra (Lopinavir and Ritonavir)

HCQ also appears to be very effective at keeping you from getting this damn thing in the first place.

Posted by Drew458     on 03/18/2020 at 09:09 PM   
Filed Under: • Health-Medicine • pandemic and epidemic diseases • Pandemic Pandemonium •  
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