One disease that no rat will ever evolve immunity against is high velocity lead poisoning.
And I hate to say I Told Ya So, but I did. First the trash piles up. Then come the rats. Then comes the plague.
I thought socialism attracts rats?
Hey, you can cook them. If you get past the ickyness of the fact that it’s a rat, they are an edible protein source. And they get pretty big. Nobody ever eat “bushy-tail tree-rat” here? It’s food, if you need food. I’ve seen people starve to death in the midst of plenty, because of “sensibilities” or lack of knowledge.
Mind you, I would attempt to avoid city rats. Country rats, while still rats, are not nearly as disgusting in their consumption habits. But if you’re hungry, it’s protein.
A former colleague caught Weils disease from working in areas where rats run. A very nasty disease if not caught in time. Recently a half-witted woman in the UK “rescued” a rat and was bitten for her trouble. She subsequently died. I’m with Drew the best solution is lead at high velocity.